The Syrian hamster model of hantavirus pulmonary syndrome
نویسندگان
چکیده
منابع مشابه
Maporal viral infection in the Syrian golden hamster: a model of hantavirus pulmonary syndrome.
Hantavirus pulmonary syndrome (HPS) is a severe and often fatal rodent-borne zoonosis. Maporal (MAP) virus is a newly discovered hantavirus that originally was isolated from an arboreal rice rat captured in central Venezuela. The results of this study indicate that MAP virus in the Syrian golden hamster (Mesocricetus auratus) can cause a disease that is clinically and pathologically remarkably ...
متن کاملT cells are not required for pathogenesis in the Syrian hamster model of hantavirus pulmonary syndrome.
Andes virus (ANDV) is associated with a lethal vascular leak syndrome in humans termed hantavirus pulmonary syndrome (HPS). In hamsters, ANDV causes a respiratory distress syndrome closely resembling human HPS. The mechanism for the massive vascular leakage associated with HPS is poorly understood; however, T cell immunopathology has been implicated on the basis of circumstantial and corollary ...
متن کاملHantavirus pulmonary syndrome.
Hantavirus pulmonary syndrome (HPS) is a severe disease characterized by a rapid onset of pulmonary edema followed by respiratory failure and cardiogenic shock. The HPS associated viruses are members of the genus Hantavirus, family Bunyaviridae. Hantaviruses have a worldwide distribution and are broadly split into the New World hantaviruses, which includes those causing HPS, and the Old World h...
متن کاملHantavirus pulmonary syndrome.
Hantavirus pulmonary syndrome, also known as hantavirus cardiopulmonary syndrome, is a recently described infectious syndrome found throughout the Americas. Although infection is sporadic and uncommon compared with other atypical pneumonia syndromes, its high mortality rate warrants the maintenance of a high index of suspicion in rural settings. Because no specific therapies are available for t...
متن کاملHantavirus pulmonary syndrome.
An outbreak of Hantavirus Pulmonary Syndrome (HPS) occurred in the western U.S. in 1993. This outbreak was surprising because serious disease due to hantavirus had not been reported previously in the U.S., and hantavirus had not been documented to cause significant pulmonary disease. Epidemiologic investigation discovered a novel strain of hantavirus as the etiologic agent of HPS. The Centers f...
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ژورنال
عنوان ژورنال: Antiviral Research
سال: 2012
ISSN: 0166-3542
DOI: 10.1016/j.antiviral.2012.06.002